17-OH progesterone shine bambancin matsakaici na kira na hormones adrenal: glucocorticoids, estrogens da androgens. 17-ON progesterone tana nufin jinsin namiji. A cikin jikin mace, hawan 17-OH ne ake samar da shi daga adrenals da ovaries.
Halin sakamako na 17-OH ya cigaba da jikin jikin mace
A cikin mace a cikin jiki, cututtukan 17-OH na shafar yiwuwar tsarawa da kuma lokacin gestation, yayin da wannan hormone ke shiga cikin aikin haihuwa. Bugu da ƙari, namiji na namiji a cikin jikin mace yana taka rawar a farkon tsufa, suna da alhakin sāke canjin hormones cikin estrogens. A cikin jikin mace, ana haifar da hormones na namiji fiye da maza. Amma idan suka kara sama da matakin ilimin lissafi, hyperandrogenia tasowa. A mafi yawan lokuta, ana gano wannan alamar kafin kafin lokacin haihuwa.
Kwanan adadin 17-OH haɗari
Matakan hakar mai-hamsin hamsin (17-OH) ya tashi a farkon lokacin haihuwar jariri, musamman idan an haife shi ba tare da daɗewa ba. Bayan makon farko na rayuwar jariri, matakin hormone ya rage kuma ya kasance har sai lokacin haihuwa ya fara. Bayan an fara tsufa, matakin kwayar cutar 17-OH ya kai ga matakin hormone a cikin manya:
- 0.2 - 2.3 ng / ml a cikin maza;
- 0.2 - 1.2 ng / ml a cikin mata a cikin lokaci na follicular;
- 1.0 - 4.5 ng / ml cikin mata a cikin lokaci na luteal;
- 2.0 - 12.0 ng / ml a cikin mata masu ciki.
17-OH haɓakar ƙira - haɗari
Dalili na kara yawan kwayar cutar 17-OH na iya kasancewar kasancewar alamun irin su:
- na al'ada adrenal hyperplasia;
- rashi na 21-hydroxylase da 11-b hydroxylase;
- ciwacen ƙwayoyi na ovaries da adrenal gland.
An yi la'akari da matakan da aka hawanta na 17-OH a yayin daukar ciki, wanda shine ka'idar farfadowa. Idan an hawan sama da hamsin-hamsin hamsin na OH fiye da lokacin ciki, to sai ku nemi shawara ga likitan don shawara kuma kuyi gwaje-gwaje don hormones.
17-OH haɓaka mai karuwa - bayyanar cututtuka
Matakan da ke cikin kwayar cutar ta 17-OH zai iya haifar da irin wannan cututtuka a cikin mata:
- wuce haddi gashi girma da thinning;
- rashin ko haila na al'ada;
- cin zarafin jini sugar;
- kuraje .
Idan babu isasshen farfadowa, irin waɗannan cututtuka na iya cigaba da ci gaba da ɓarna, kamar:
- cin zarafin insulin;
- ciwon sukari mellitus;
- hawan jini;
- ƙãra cholesterol;
- matsaloli da zuciya.
A gaban ciwon ciwo na ovary polycystic, za a iya ƙara yawan kwayar cutar hormone 17-OH, sabili da haka, a gano wannan cutar yana da muhimmanci don yin gwaje-gwaje don hormones.
Babban hawan 17-OH na haɗari da hawaye
Daya daga cikin bayyanar cututtuka na haɓaka 17-OH shine cututtuka na fata ko pimples. Lokacin da matakin wannan hormone ya ragu, alamar bayyanar ta tafi. Saboda haka, a lokacin da ake magance wannan matsalar dermatological, dole ne a yi amfani da maƙasudin hanyoyi na gida kawai, amma har ila yau ya daidaita tsarin asalin hormonal.
Yadda za a rage yawan haɓaka 17-OH?
Yin jiyya tare da matakin da aka haɓaka da kwayar cutar 17-OH ne ake aiwatarwa ta kwayoyin hormonal. Alal misali, dexamethasone ko methylprednisolone. Lokacin shan wadannan magungunan, akwai wasu ƙwarewa, saboda suna riƙe da ruwa. Babu wani sakamako masu illa, saboda a lura da rashin haihuwa
Kwararrun magani da karɓar maganin kwayoyi sunadaita ta likita dangane da bayyanuwar cututtuka na asibiti, abubuwan da suka faru na juyayi. Ya kamata a raba kashi na yau da kullum zuwa yawan asurai. Lokaci tsakanin shan magani ya zama daidai. Zaka iya ɗaukar shan magani bayan cin abinci, idan akwai matsaloli tare da gastrointestinal tract. Lokaci-lokaci, kana buƙatar ɗaukar gwaji, duba matakin hormone da tasirin magani.
Tare da rashin haihuwa kafin lokacin da aka fara ciki, hanya na magani zai iya wucewa daga watanni uku zuwa shida.