Bilirubin shi ne bile pigment, wanda shine samfurin kayan aiki na rushe tsohuwar jini. Yawanci, mai girma a cikin ƙwayar jini yana dauke da ƙananan adadin wannan abu (3,4 - 22,2 μmol / l), kuma wasu adadin fitsari a cikin nau'i na urobilinogens (4 MG) kowace rana.
Kimanin kashi 96 cikin 100 na bilirubin a cikin jini shi ne bilirubin mai kai tsaye, wanda ba shi da ruwa a cikin ruwa kuma yana da guba, saboda zai iya shiga cikin tantanin halitta kuma ya rushe muhimmancin kwayoyin halitta. Sauran sauran kashi 4% na bilirubin ne kawai, mai narkewa a cikin ruwa, da kodan da aka sarrafa ya kuma cire shi a cikin fitsari. Jimlar bilirubin ita ce matakin janar bilirubin na kai tsaye da kai tsaye.
A wasu cututtuka, abun ciki na bilirubin cikin jini, da kuma ci gaba a cikin fitsari, yana ƙaruwa. Wannan yana haifar da jaundice da darkening na fitsari.
Dalilin matakan bilirubin da aka hawanta a cikin manya
Bari muyi la'akari, me yasa dalilai na kowa ko na kowa bilirubin a jikin kwayoyin mutum zasu iya tasowa ko ƙarawa.
Dalilin ƙara yawan bilirubin
Matsayin bilirubin na tsaye a cikin jini ya karu saboda rashin cin zarafin bile. A sakamakon haka, an aiko bile zuwa jini, ba cikin ciki ba. Dalilin da wannan shine mafi yawan lokuta wadannan pathologies:
- hepatitis na ilimin ilimin lissafi na kwayar halitta a cikin mummunan tsari (hepatitis A, B, tare da mononucleosis na jini);
- hepatitis na ilmin kwayoyin kwayoyin halitta (leptospirosis, brucellosis);
- na kullum hepatitis;
- Hanyoyin hepatitis na autoimmune;
- ilpatitis na magani (sakamakon sakamako na hormone, wadanda ba kwayoyi masu tsai da cututtukan steroidal, magungunan antitumor da magungunan maganin tarin fuka);
- da ciwon guba mai guba (guba tare da furotin, masana'antu masu guba);
- ciwon daji na gallbladder, hanta ko pancreas;
- cholelithiasis;
- biliary cirrhosis;
- Yanayin Rotor, Dabin-Johnson.
Sanadin bilirubin ya karu
Ƙarawa a cikin abun ciki na bilirubin wanda ba a kai tsaye ba zai iya haɗuwa da ƙaddamar da cututtukan jini ko kuma ta katsewa a cikin aiki na bilirubin mai kai tsaye. Yana da daraja lura cewa, tun da bilirubin mai kai tsaye a cikin ruwa ba zai rushe ba, har ma tare da karuwa mai karuwa a matakinsa a cikin jini, babu wata karkatawa cikin bincike na fitsari. Saboda haka, dalilai na wannan zai iya zama:
- Anemia wanda ke dauke da kwayar cutar (sikila, spherocytic, nesferocytic, thallasemia, cutar Marciyafawa-Michele);
- abar sakandare na biyu (gameda cutar arthritis, tsarin lupus erythematosus, lymphocytic cutar sankarar bargo, lymphanganulmatosis, da dai sauransu);
- magungunan hemolytic na magani (dangantaka da insulin, aspirin, levomycetin, levofloxacin, cephalosporins, da sauransu);
- raunuka na Lucy-Driskol, Gilbert, Kriegler-Nayyar;
- cututtuka (malaria, typhoid, sepsis);
- anemia mai yalwa mai guba ( guba tare da namomin kaza mai guba, poisons, cizon kwari, maciji, guba tare da namomin kaza, gubar, jan salts, da sauransu).
Dalilin karuwar bilirubin a ciki
An kara yawan bilirubin a cikin mata masu ciki (jaundice a ciki). Dalili akan wannan an raba shi zuwa kungiyoyi biyu:
- saboda yanayin da ake ciki na ciki (mummunan lalacewa na hanta, gestosis, zubar da ciki, da dai sauransu);
- ya haifar da cututtukan cututtuka masu yawa (hepatitis, hememytic anemia, da dai sauransu).
Sanadin matsalar bilirubin da yawa a cikin fitsari
An kara yawan bilirubin cikin gaggawa a cikin cututtuka tare da lalacewar hanta
- hepatitis;
- cirrhosis na hanta ;
- Hanyar hanta na cin zarafi;
- hanta rauni, da dai sauransu.
Jiyya na bilirubin hawan
Idan gwaje-gwajen ya nuna cewa bilirubin a cikin jini ko a cikin fitsari yana daukaka, ka'idodin magani zai danganta ne akan haddasa wannan farfadowa. Yawanci, hanyoyin warkewa sun hada da shan magunguna da daidaita gashin abinci.